BOston Neonatal Brain Injury Data for Hypoxic Ischemic Encephalopathy (BONBID-HIE): I. MRI and Lesion Labeling
Abstract Hypoxic ischemic encephalopathy (HIE) is a brain injury that occurs in 1 ~ 5/1000 term neonates. Accurate identification and segmentation of HIE-related lesions in neonatal brain magnetic resonance images (MRIs) is the first step toward identifying high-risk patients, understanding neurolog...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2025-01-01
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| Series: | Scientific Data |
| Online Access: | https://doi.org/10.1038/s41597-024-03986-7 |
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| author | Rina Bao Ya’nan Song Sara V. Bates Rebecca J. Weiss Anna N. Foster Camilo Jaimes Susan Sotardi Yue Zhang Randy L. Hirschtick P. Ellen Grant Yangming Ou |
| author_facet | Rina Bao Ya’nan Song Sara V. Bates Rebecca J. Weiss Anna N. Foster Camilo Jaimes Susan Sotardi Yue Zhang Randy L. Hirschtick P. Ellen Grant Yangming Ou |
| author_sort | Rina Bao |
| collection | DOAJ |
| description | Abstract Hypoxic ischemic encephalopathy (HIE) is a brain injury that occurs in 1 ~ 5/1000 term neonates. Accurate identification and segmentation of HIE-related lesions in neonatal brain magnetic resonance images (MRIs) is the first step toward identifying high-risk patients, understanding neurological symptoms, evaluating treatment effects, and predicting outcomes. We release the first public dataset containing neonatal brain diffusion MRI and expert annotation of lesions from 133 patients diagnosed with HIE. HIE-related lesions in brain MRI are often diffuse (i.e., multi-focal), and small (over half the patients in our data having lesions occupying <1% of the brain volume (including ventricles)). Segmentation for HIE MRI data is remarkably different from, and arguably more challenging than, other segmentation tasks such as brain tumors with focal and relatively large lesions. We hope that this dataset can help fuel the development of MRI lesion segmentation methods for HIE and small diffuse lesions in general. |
| format | Article |
| id | doaj-art-123897a252af43179b6e6457386ab58d |
| institution | Kabale University |
| issn | 2052-4463 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Data |
| spelling | doaj-art-123897a252af43179b6e6457386ab58d2025-01-12T12:07:33ZengNature PortfolioScientific Data2052-44632025-01-0112111110.1038/s41597-024-03986-7BOston Neonatal Brain Injury Data for Hypoxic Ischemic Encephalopathy (BONBID-HIE): I. MRI and Lesion LabelingRina Bao0Ya’nan Song1Sara V. Bates2Rebecca J. Weiss3Anna N. Foster4Camilo Jaimes5Susan Sotardi6Yue Zhang7Randy L. Hirschtick8P. Ellen Grant9Yangming Ou10Boston Children’s HospitalBoston Children’s HospitalHarvard Medical SchoolBoston Children’s HospitalBoston Children’s HospitalHarvard Medical SchoolBoston Children’s HospitalBoston Children’s HospitalHarvard Medical SchoolBoston Children’s HospitalBoston Children’s HospitalAbstract Hypoxic ischemic encephalopathy (HIE) is a brain injury that occurs in 1 ~ 5/1000 term neonates. Accurate identification and segmentation of HIE-related lesions in neonatal brain magnetic resonance images (MRIs) is the first step toward identifying high-risk patients, understanding neurological symptoms, evaluating treatment effects, and predicting outcomes. We release the first public dataset containing neonatal brain diffusion MRI and expert annotation of lesions from 133 patients diagnosed with HIE. HIE-related lesions in brain MRI are often diffuse (i.e., multi-focal), and small (over half the patients in our data having lesions occupying <1% of the brain volume (including ventricles)). Segmentation for HIE MRI data is remarkably different from, and arguably more challenging than, other segmentation tasks such as brain tumors with focal and relatively large lesions. We hope that this dataset can help fuel the development of MRI lesion segmentation methods for HIE and small diffuse lesions in general.https://doi.org/10.1038/s41597-024-03986-7 |
| spellingShingle | Rina Bao Ya’nan Song Sara V. Bates Rebecca J. Weiss Anna N. Foster Camilo Jaimes Susan Sotardi Yue Zhang Randy L. Hirschtick P. Ellen Grant Yangming Ou BOston Neonatal Brain Injury Data for Hypoxic Ischemic Encephalopathy (BONBID-HIE): I. MRI and Lesion Labeling Scientific Data |
| title | BOston Neonatal Brain Injury Data for Hypoxic Ischemic Encephalopathy (BONBID-HIE): I. MRI and Lesion Labeling |
| title_full | BOston Neonatal Brain Injury Data for Hypoxic Ischemic Encephalopathy (BONBID-HIE): I. MRI and Lesion Labeling |
| title_fullStr | BOston Neonatal Brain Injury Data for Hypoxic Ischemic Encephalopathy (BONBID-HIE): I. MRI and Lesion Labeling |
| title_full_unstemmed | BOston Neonatal Brain Injury Data for Hypoxic Ischemic Encephalopathy (BONBID-HIE): I. MRI and Lesion Labeling |
| title_short | BOston Neonatal Brain Injury Data for Hypoxic Ischemic Encephalopathy (BONBID-HIE): I. MRI and Lesion Labeling |
| title_sort | boston neonatal brain injury data for hypoxic ischemic encephalopathy bonbid hie i mri and lesion labeling |
| url | https://doi.org/10.1038/s41597-024-03986-7 |
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