Safety and efficacy of human umbilical cord-derived mesenchymal stromal cells in fetal ovine myelomeningocele repair

Safety and efficacy of human umbilical cord-derived mesenchymal stromal cells in fetal ovine myelomeningocele repair

Abstract Background The aim of this study was to assess the safety and efficacy of human umbilical cord mesenchymal stromal cells (hUC-MSCs) patch used as an adjuvant therapy in fetal myelomeningocele (MMC) surgery in the ovine model. Methods hUC-MSCs were isolated from human umbilical cords (UC) us...

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Main Authors: Yoann Athiel, Laura Cariot, Jean-Marie Jouannic, Corentin Maillet, Vincent Mauffré, Clovis Adam, Hélène Huet, Jérôme Larghero, Justine Nasone, Lucie Guilbaud
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Stem Cell Research & Therapy
Subjects:
Myelomeningocele
Fetal repair
Umbilical cord-mesenchymal stromal cells
Safety
Efficacy
Online Access:https://doi.org/10.1186/s13287-024-03991-y
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https://doi.org/10.1186/s13287-024-03991-y

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