A non-canonical role of somatic Cyclin D/CYD-1 in oogenesis and in maintenance of reproductive fidelity, dependent on the FOXO/DAF-16 activation state.

A non-canonical role of somatic Cyclin D/CYD-1 in oogenesis and in maintenance of reproductive fidelity, dependent on the FOXO/DAF-16 activation state.

For the optimal survival of a species, an organism coordinates its reproductive decisions with the nutrient availability of its niche. Thus, nutrient-sensing pathways like insulin-IGF-1 signaling (IIS) play an important role in modulating cell division, oogenesis, and reproductive aging. Lowering of...

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Main Authors: Umanshi Rautela, Gautam Chandra Sarkar, Ayushi Chaudhary, Debalina Chatterjee, Mohtashim Rosh, Aneeshkumar G Arimbasseri, Arnab Mukhopadhyay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-11-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1011453
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https://doi.org/10.1371/journal.pgen.1011453

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