Semen Analysis of Covid-19 Survivors and Uninfected Men: Examining the Motility, Concentration, Vitality, and Morphology Parameters of Spermatozoa
Highlights: 1. Spermatozoa can be affected by coronavirus disease 2019 (COVID-19) due to a disruption in spermatogenesis, leading to a decline in semen quality. 2. This study compared the semen quality of COVID-19 survivors and those who had not been infected with COVID-19, specifically on the first...
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Universitas Airlangga
2024-09-01
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| Series: | Folia Medica Indonesiana |
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| Online Access: | https://e-journal.unair.ac.id/FMI/article/view/60199 |
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| author | Sri Musta'ina Eko Budi Siswidiyanto Pety Narulita Agustinus Aucky Hinting Atika Zakiyatul Faizah |
| author_facet | Sri Musta'ina Eko Budi Siswidiyanto Pety Narulita Agustinus Aucky Hinting Atika Zakiyatul Faizah |
| author_sort | Sri Musta'ina |
| collection | DOAJ |
| description | Highlights:
1. Spermatozoa can be affected by coronavirus disease 2019 (COVID-19) due to a disruption in spermatogenesis, leading to a decline in semen quality.
2. This study compared the semen quality of COVID-19 survivors and those who had not been infected with COVID-19, specifically on the first spermatogenesis cycle following the confirmation of COVID-19 infection.
3. This study is distinctive since no previous research in Indonesia has examined the semen quality parameters, such as the concentration, morphology, motility, and vitality of spermatozoa, in men who had a COVID-19 infection.
Abstract
Semen quality in COVID-19 patients shows inconsistencies and variations. This research was conducted considering that health is the main capital for humans in Indonesia's development, as outlined in Sustainable Development Goal 3. The purpose of this study was to compare the semen quality of COVID-19 survivors with non-COVID-19 men. This study was an analytical observational study with a cross-sectional design. Subjects were selected through consecutive sampling of up to 26 men of childbearing age who met the predetermined criteria. Semen quality assessment using the WHO Semen Analysis Guide 6th edition. Quantitative data were analyzed using SPSS. The data normality test was carried out using the Saphiro-Wilk test. Then, the data were tested by t-test from two unpaired samples and by the Mann-Whitney test. Data from semen analysis based on COVID-19 severity were tested using variant analysis (One-way ANOVA) and the Kruskal Wallis test. The normal morphology of spermatozoa in COVID-19 survivors was significantly lower (p=0.011) compared to uninfected men. Other semen quality parameters did not differ significantly, although they were lower in COVID-19 survivors. The results of the analysis also showed no significant difference in semen parameters related to COVID-19 severity (p=0.488 for progressive motility; p=0.372 for non-progressive motility; p=0.325 for total motility; p=0.707 for immotility; p=0.412 for vitality; p=0.324 for concentration; and p=0.334 for normal morphology). The study provides evidence that COVID-19 survivors have a lower normal spermatozoa morphology compared to uninfected men. However, the motility, vitality, and concentration of spermatozoa did not differ significantly between the two groups. |
| format | Article |
| id | doaj-art-11f99ba2b76545b8b332fb7c734b2b2b |
| institution | Kabale University |
| issn | 2355-8393 2599-056X |
| language | English |
| publishDate | 2024-09-01 |
| publisher | Universitas Airlangga |
| record_format | Article |
| series | Folia Medica Indonesiana |
| spelling | doaj-art-11f99ba2b76545b8b332fb7c734b2b2b2025-01-03T02:03:16ZengUniversitas AirlanggaFolia Medica Indonesiana2355-83932599-056X2024-09-0160320020810.20473/fmi.v60i3.6019958365Semen Analysis of Covid-19 Survivors and Uninfected Men: Examining the Motility, Concentration, Vitality, and Morphology Parameters of SpermatozoaSri Musta'ina0https://orcid.org/0009-0002-1123-7487Eko Budi Siswidiyanto1https://orcid.org/0000-0002-0237-2866Pety Narulita2https://orcid.org/0000-0001-9904-1336Agustinus3https://orcid.org/0000-0002-9376-8929Aucky Hinting4https://orcid.org/0000-0002-7955-6452Atika5Zakiyatul Faizah6https://orcid.org/0000-0003-0962-9123Department of Medical Biology, Faculty of Medicine, Universitas Airlangga, SurabayaAndrology Specialist Study Program, Faculty of Medicine, Universitas Airlangga, SurabayaAndrology Outpatient Clinic Dr. Soetomo General Academic Hospital, SurabayaDepartment of Medical Biology, Faculty of Medicine, Universitas Airlangga, SurabayaDepartment of Medical Biology, Faculty of Medicine, Universitas Airlangga, SurabayaDepartment of Public Health and Preventive Medicine, Faculty of Medicine, Universitas Airlangga, SurabayaDepartment of Medical Biology, Faculty of Medicine, Universitas Airlangga, SurabayaHighlights: 1. Spermatozoa can be affected by coronavirus disease 2019 (COVID-19) due to a disruption in spermatogenesis, leading to a decline in semen quality. 2. This study compared the semen quality of COVID-19 survivors and those who had not been infected with COVID-19, specifically on the first spermatogenesis cycle following the confirmation of COVID-19 infection. 3. This study is distinctive since no previous research in Indonesia has examined the semen quality parameters, such as the concentration, morphology, motility, and vitality of spermatozoa, in men who had a COVID-19 infection. Abstract Semen quality in COVID-19 patients shows inconsistencies and variations. This research was conducted considering that health is the main capital for humans in Indonesia's development, as outlined in Sustainable Development Goal 3. The purpose of this study was to compare the semen quality of COVID-19 survivors with non-COVID-19 men. This study was an analytical observational study with a cross-sectional design. Subjects were selected through consecutive sampling of up to 26 men of childbearing age who met the predetermined criteria. Semen quality assessment using the WHO Semen Analysis Guide 6th edition. Quantitative data were analyzed using SPSS. The data normality test was carried out using the Saphiro-Wilk test. Then, the data were tested by t-test from two unpaired samples and by the Mann-Whitney test. Data from semen analysis based on COVID-19 severity were tested using variant analysis (One-way ANOVA) and the Kruskal Wallis test. The normal morphology of spermatozoa in COVID-19 survivors was significantly lower (p=0.011) compared to uninfected men. Other semen quality parameters did not differ significantly, although they were lower in COVID-19 survivors. The results of the analysis also showed no significant difference in semen parameters related to COVID-19 severity (p=0.488 for progressive motility; p=0.372 for non-progressive motility; p=0.325 for total motility; p=0.707 for immotility; p=0.412 for vitality; p=0.324 for concentration; and p=0.334 for normal morphology). The study provides evidence that COVID-19 survivors have a lower normal spermatozoa morphology compared to uninfected men. However, the motility, vitality, and concentration of spermatozoa did not differ significantly between the two groups.https://e-journal.unair.ac.id/FMI/article/view/60199coronavirus disease 2019 (covid-19) survivorsspermatogenesisejaculate qualitycovid-19 severityhuman and and health |
| spellingShingle | Sri Musta'ina Eko Budi Siswidiyanto Pety Narulita Agustinus Aucky Hinting Atika Zakiyatul Faizah Semen Analysis of Covid-19 Survivors and Uninfected Men: Examining the Motility, Concentration, Vitality, and Morphology Parameters of Spermatozoa Folia Medica Indonesiana coronavirus disease 2019 (covid-19) survivors spermatogenesis ejaculate quality covid-19 severity human and and health |
| title | Semen Analysis of Covid-19 Survivors and Uninfected Men: Examining the Motility, Concentration, Vitality, and Morphology Parameters of Spermatozoa |
| title_full | Semen Analysis of Covid-19 Survivors and Uninfected Men: Examining the Motility, Concentration, Vitality, and Morphology Parameters of Spermatozoa |
| title_fullStr | Semen Analysis of Covid-19 Survivors and Uninfected Men: Examining the Motility, Concentration, Vitality, and Morphology Parameters of Spermatozoa |
| title_full_unstemmed | Semen Analysis of Covid-19 Survivors and Uninfected Men: Examining the Motility, Concentration, Vitality, and Morphology Parameters of Spermatozoa |
| title_short | Semen Analysis of Covid-19 Survivors and Uninfected Men: Examining the Motility, Concentration, Vitality, and Morphology Parameters of Spermatozoa |
| title_sort | semen analysis of covid 19 survivors and uninfected men examining the motility concentration vitality and morphology parameters of spermatozoa |
| topic | coronavirus disease 2019 (covid-19) survivors spermatogenesis ejaculate quality covid-19 severity human and and health |
| url | https://e-journal.unair.ac.id/FMI/article/view/60199 |
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