Apocynin, a Selective NADPH Oxidase (Nox2) Inhibitor, Ameliorates Behavioural and Learning Deficits in the Fragile X Syndrome Mouse Model

Apocynin, a Selective NADPH Oxidase (Nox2) Inhibitor, Ameliorates Behavioural and Learning Deficits in the Fragile X Syndrome Mouse Model

<b>Background/Objectives:</b> Fragile X Syndrome (FXS) is associated with intellectual disability, hyperactivity, social anxiety and signs of autism. Hyperactivation of NADPH oxidase has been previously described in the brain of the male <i>Fmr1</i>-KO mouse. This work aims t...

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Bibliographic Details
Main Authors: Yolanda de Diego-Otero, Rajaa El Bekay, Francisco García-Guirado, Lourdes Sánchez-Salido, Rosa María Giráldez-Pérez
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Biomedicines
Subjects:
fragile X syndrome
Apocynin
NADPH-oxidase
hyperactivity
behaviour
learning
Online Access:https://www.mdpi.com/2227-9059/12/12/2887
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