Deep phenotyping of a modified diabetic cardiomyopathy mouse model which reflects clinical disease progression

Deep phenotyping of a modified diabetic cardiomyopathy mouse model which reflects clinical disease progression

Abstract Diabetic cardiomyopathy (DbCM) is a progressive disease and common complication of metabolic diabetes. It is characterised by onset of cardiac structural and functional impairments and can lead to direct development of clinical heart failure (HF) or predispose to hypertensive/ischaemic stre...

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Main Authors: Narainrit Karuna, Lauren Kerrigan, Kevin Edgar, Oisin Cappa, David Simpson, Claire Tonry, David J. Grieve, Chris J. Watson
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Diabetic cardiomyopathy
Metabolic syndrome
Diastolic dysfunction
Heart failure
Cardiac fibrosis
Online Access:https://doi.org/10.1186/s13098-025-01913-3
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https://doi.org/10.1186/s13098-025-01913-3

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