AMPA receptor diffusional trapping machinery as an early therapeutic target in neurodegenerative and neuropsychiatric disorders

AMPA receptor diffusional trapping machinery as an early therapeutic target in neurodegenerative and neuropsychiatric disorders

Abstract Over the past two decades, there has been a growing recognition of the physiological importance and pathological implications surrounding the surface diffusion of AMPA receptors (AMPARs) and their diffusional trapping at synapses. AMPAR surface diffusion entails the thermally powered random...

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Bibliographic Details
Main Authors: Daniel Choquet, Patricio Opazo, Hongyu Zhang
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Translational Neurodegeneration
Subjects:
AMPA receptors
Diffusional trapping
Huntington’s disease
Alzheimer’s disease
Stress
Depression
Online Access:https://doi.org/10.1186/s40035-025-00470-z
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https://doi.org/10.1186/s40035-025-00470-z

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