Nuclear factor I-C regulates enamel and dentin formation via the Sonic hedgehog signaling pathway in mouse incisors

Nuclear factor I-C regulates enamel and dentin formation via the Sonic hedgehog signaling pathway in mouse incisors

Abstract Background Tooth development involves interactions between epithelium and mesenchyme conducted via multiple signaling molecules. This study aimed to investigate the roles of Nuclear factor I-C (NFIC) and Sonic hedgehog (SHH) in regulating enamel and dentin formation in mouse incisors. Metho...

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Bibliographic Details
Main Authors: Rui Zhang, Ruiqi Li, Xiaofeng Huang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Oral Health
Subjects:
Tooth development
NFIC
SHH
Incisor
Dentin formation
Enamel
Online Access:https://doi.org/10.1186/s12903-025-06276-9
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https://doi.org/10.1186/s12903-025-06276-9

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