Analyses of the mechanism and therapeutic targets of senescence related genes in ischemic stroke with multi-omics approach

Analyses of the mechanism and therapeutic targets of senescence related genes in ischemic stroke with multi-omics approach

Abstract Ischemic stroke (IS) affects 11 million people annually, posing substantial clinical and economic burdens. Current therapies remain limited by time sensitivity and variable efficacy, necessitating novel biomarkers. We developed a multi-omics framework to investigate senescence-associated ge...

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Bibliographic Details
Main Authors: Nanding Li, Shanquan Jing, Kang An, Bo Jia, Yingjie Han, Zan Wang, Chengcai Li, Xiaole Li, Jiwei Wang, Wei Liu, Conghui Li
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Ischemic stroke
Senescence related genes
Biomarkers
Multi-omics
Immune profiling
Therapeutic targets
Online Access:https://doi.org/10.1038/s41598-025-10367-6
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https://doi.org/10.1038/s41598-025-10367-6

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