Investigating interassay variability between direct oral anticoagulant calibrated anti–factor Xa assays: a substudy of the perioperative anticoagulation use for surgery evaluation (PAUSE) trial

Investigating interassay variability between direct oral anticoagulant calibrated anti–factor Xa assays: a substudy of the perioperative anticoagulation use for surgery evaluation (PAUSE) trial

Background: Direct oral anticoagulant calibrated anti-factor Xa (FXa) assays can assess residual anticoagulant levels in patients requiring urgent procedures or surgery. However, previous studies have shown variability between anti-FXa levels determined by different instrument-reagent combinations....

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Bibliographic Details
Main Authors: Ryan M. Baker, Rita Selby, Karen A. Moffat, Melanie St John, Alex C. Spyropoulos, Sam Schulman, James Douketis
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
apixaban
blood coagulation tests
clinical laboratory techniques
factor Xa inhibitors
rivaroxaban
Online Access:http://www.sciencedirect.com/science/article/pii/S2475037925002237
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