Deficiency in intestinal epithelial O‐GlcNAcylation predisposes to gut inflammation
Abstract Post‐translational modifications in intestinal epithelial cells (IECs) allow for precise control in intestinal homeostasis, the breakdown of which may precipitate the pathological damage and inflammation in inflammatory bowel disease. The O‐linked β‐N‐acetylglucosamine (O‐GlcNAc) modificati...
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| Main Authors: | Ming Zhao, Xiwen Xiong, Kaiqun Ren, Bing Xu, Meng Cheng, Chinmayi Sahu, Kaichun Wu, Yongzhan Nie, Zan Huang, Richard S Blumberg, Xiaonan Han, Hai‐Bin Ruan |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2018-06-01
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| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/emmm.201708736 |
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