Construction of chimeric IL-21 recombinant oncolytic influenza virus and mechanisms for its antitumor efficacy against hepatocellular carcinoma

Objective To rescue a recombinant oncolytic influenza virus chimeric with IL-21 and evaluate its inhibitory effects and safety against hepatocellular carcinoma (HCC) both in vitro and in vivo, and to explore the mechanism by which this virus enhances antitumor effects when combined with anti-program...

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Bibliographic Details
Main Authors: CAO Rui, ZENG Guineng, TIAN Yuying
Format: Article
Language:zho
Published: Editorial Office of Journal of Army Medical University 2024-12-01
Series:陆军军医大学学报
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Online Access:https://aammt.tmmu.edu.cn/html/202407051.htm
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