Mechanisms of pulmonary fibrosis and lung cancer induced by chronic PM2.5 exposure: Focus on the airway epithelial barrier and epithelial-mesenchymal transition

Mechanisms of pulmonary fibrosis and lung cancer induced by chronic PM2.5 exposure: Focus on the airway epithelial barrier and epithelial-mesenchymal transition

This study aims to provide new insights into PM2.5-induced lung diseases through a focus on the pulmonary epithelial barrier and epithelial-mesenchymal transition (EMT). Firstly, we analyzed the mechanisms by which PM2.5 damages the airway epithelial barrier, including inflammatory responses, immune...

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Bibliographic Details
Main Authors: Yuyu Shi, Qi Shao, Zilin Ren, Guojiao Shang, Jinhua Han, Jialin Cheng, Yuxiao Zheng, Fafeng Cheng, Changxiang Li, Qingguo Wang, Xueqian Wang
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Ecotoxicology and Environmental Safety
Subjects:
PM2.5
Epithelial barrier
EMT
Lung injury
Drug therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325005895
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http://www.sciencedirect.com/science/article/pii/S0147651325005895

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