Deciphering the angiogenic potential of Zhishi Xiebai Guizhi decoction in coronary heart disease: an in-depth network pharmacology and experimental investigation

Deciphering the angiogenic potential of Zhishi Xiebai Guizhi decoction in coronary heart disease: an in-depth network pharmacology and experimental investigation

Abstract ZXGD Decoction, a traditional Chinese formulation historically used for cardiovascular ailments, was evaluated for its efficacy in coronary heart disease (CHD) through an integrated network pharmacology and randomized controlled trial (RCT) approach. Its selection was rooted in documented t...

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Bibliographic Details
Main Authors: Yingli Mo, Yuping Xu, Bei Lu, Xiaojuan Fan, Qingshuang Zhang, Shaowu Cheng, Qinghua Peng
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Network pharmacology
Zhishi Xiebai Guizhi decoction
Coronary heart disease
Angiogenesis
Traditional Chinese medicine
Zebrafish
Online Access:https://doi.org/10.1038/s41598-025-05379-1
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https://doi.org/10.1038/s41598-025-05379-1

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