Glial Cells in Spinal Muscular Atrophy: Speculations on Non-Cell-Autonomous Mechanisms and Therapeutic Implications

Glial Cells in Spinal Muscular Atrophy: Speculations on Non-Cell-Autonomous Mechanisms and Therapeutic Implications

Spinal muscular atrophy (SMA) is a neuromuscular disorder caused by homozygous deletions or mutations in the <i>SMN1</i> gene, leading to progressive motor neuron degeneration. While SMA has been classically viewed as a motor neuron-autonomous disease, increasing evidence indicates a sig...

Full description

Saved in:
Bibliographic Details
Main Authors: Andrej Belančić, Tamara Janković, Elvira Meni Maria Gkrinia, Iva Kristić, Jelena Rajič Bumber, Valentino Rački, Kristina Pilipović, Dinko Vitezić, Jasenka Mršić-Pelčić
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Neurology International
Subjects:
spinal muscular atrophy
glial cells
neuroinflammation
synaptic dysfunction
myelination
Online Access:https://www.mdpi.com/2035-8377/17/3/41
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/2035-8377/17/3/41

Similar Items