The adhesion mechanism of mucoadhesive tablets with dissimilar chain flexibility on viscoelastic hydrogels

Mucosal membranes with strong variability in their viscoelastic properties line numerous organs and are often targeted by mucoadhesive formulations, e.g., highly swellable hydroxypropylmethylcellulose (HPMC) and slightly cross-linked poly(acrylic acid) (PAA) tablets. Although the factors determining...

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Bibliographic Details
Main Authors: Gergely Stankovits, Kata Szayly, Dorián László Galata, János Móczó, András Szilágyi, Benjámin Gyarmati
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Materials Today Bio
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Online Access:http://www.sciencedirect.com/science/article/pii/S2590006424004770
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