Probing spatiotemporally organized GPCR signaling using genetically encoded molecular tools

Abstract G-protein-coupled receptors (GPCRs) control various downstream signaling pathways, with multiple effectors whose interactions are subject to sophisticated regulation to achieve signaling specificity. Spatiotemporal organization of GPCR signaling is essential for efficient control of multifa...

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Bibliographic Details
Main Authors: Yonghoon Kwon, Sohum Mehta, Jin Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-025-01485-2
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