Extending Investigations of miR‐126‐5p on the Regulation of CYP2A6, the Major Nicotine‐Inactivating Enzyme

ABSTRACT CYP2A6 is the hepatic enzyme responsible for the metabolic inactivation of nicotine. Variation in CYP2A6 alters nicotine clearance, affecting numerous smoking behaviors and tobacco‐related diseases, making investigating sources of variation important. A published molecular study of microRNA...

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Bibliographic Details
Main Authors: Weilong Gu, Alec W. R. Langlois, Haidy Giratallah, Katrina G. Claw, Bhagwat Prasad, Kenneth E. Thummel, Rachel F. Tyndale
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Pharmacology Research & Perspectives
Online Access:https://doi.org/10.1002/prp2.70149
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