CD22 blockade exacerbates neuroinflammation in Neuromyelitis optica spectrum disorder

CD22 blockade exacerbates neuroinflammation in Neuromyelitis optica spectrum disorder

Abstract Background Neuromyelitis optica spectrum disorder (NMOSD) is an autoantibody-triggered central nervous system (CNS) demyelinating disease that primarily affects the spinal cord, optic nerves and brainstem. Among the first responders to CNS injury, microglia are prominent players that drive...

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Main Authors: Wenjun Zhang, Yali Han, Huachen Huang, Yue Su, Honglei Ren, Caiyun Qi, Jinyi Li, Huaijin Yang, Jing Xu, Guoqiang Chang, Wenjin Qiu, Qiang Liu, Ting Chang
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Neuroinflammation
Subjects:
CD22
Microglia
Neuroinflammation
Neuromyelitis optica spectrum disorder
Demyelination
Online Access:https://doi.org/10.1186/s12974-024-03305-2
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https://doi.org/10.1186/s12974-024-03305-2

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