Potential for the Bio-Detoxification of the Mycotoxins Enniatin B and Deoxynivalenol by Lactic Acid Bacteria and <i>Bacillus</i> spp.

Mycotoxins, toxic compounds produced by fungi, pose significant risks to food safety and human health. This study investigates the bio-detoxification potential of 238 strains of lactic acid bacteria (LAB) and <i>Bacillus</i> spp., previously isolated from cereals (including mycotoxin-con...

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Main Authors: Sandra Mischler, Amandine André, Irene Chetschik, Susanne Miescher Schwenninger
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Microorganisms
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Online Access:https://www.mdpi.com/2076-2607/12/9/1892
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author Sandra Mischler
Amandine André
Irene Chetschik
Susanne Miescher Schwenninger
author_facet Sandra Mischler
Amandine André
Irene Chetschik
Susanne Miescher Schwenninger
author_sort Sandra Mischler
collection DOAJ
description Mycotoxins, toxic compounds produced by fungi, pose significant risks to food safety and human health. This study investigates the bio-detoxification potential of 238 strains of lactic acid bacteria (LAB) and <i>Bacillus</i> spp., previously isolated from cereals (including mycotoxin-contaminated grains), against the emerging mycotoxin, enniatin B (ENB), and the prevalent mycotoxin, deoxynivalenol (DON). Out of the tested strains, 26 demonstrated notable mycotoxin reduction capabilities, including 2 <i>Bacillus pumilus</i> and 24 <i>Bacillus licheniformis</i> strains. <i>B. licheniformis</i> strains MA572, MA695, MA696, TR174a, TR284, TR363, and TR466a degraded ENB to levels below the detection limit, and six strains reduced DON by 30–35%; <i>B. licheniformis</i> TR251b and TR374 showed the highest DON reduction with 35.7%. The most promising strains for bio-detoxification were <i>B. licheniformis</i> TR284, which achieved a 100% reduction in ENB and a 28.6% reduction in DON and <i>B. licheniformis</i> TR388 with a 97.5% reduction in ENB and a 31.9% reduction in DON. None of the tested LAB strains significantly reduced either mycotoxin. These findings highlight the promising potential of <i>B. licheniformis</i> strains in bio-detoxifying mycotoxin-contaminated cereal products. Further research into the underlying detoxification mechanisms and safety aspects is essential to develop effective bio-detoxification strategies for enhancing food safety.
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spelling doaj-art-0ce68c381fe34f05a98aeaf24f3f7d082025-08-20T01:55:41ZengMDPI AGMicroorganisms2076-26072024-09-01129189210.3390/microorganisms12091892Potential for the Bio-Detoxification of the Mycotoxins Enniatin B and Deoxynivalenol by Lactic Acid Bacteria and <i>Bacillus</i> spp.Sandra Mischler0Amandine André1Irene Chetschik2Susanne Miescher Schwenninger3Institute of Food and Beverage Innovation, ZHAW Zurich University of Applied Sciences, 8820 Wädenswil, SwitzerlandInstitute of Food and Beverage Innovation, ZHAW Zurich University of Applied Sciences, 8820 Wädenswil, SwitzerlandInstitute of Food and Beverage Innovation, ZHAW Zurich University of Applied Sciences, 8820 Wädenswil, SwitzerlandInstitute of Food and Beverage Innovation, ZHAW Zurich University of Applied Sciences, 8820 Wädenswil, SwitzerlandMycotoxins, toxic compounds produced by fungi, pose significant risks to food safety and human health. This study investigates the bio-detoxification potential of 238 strains of lactic acid bacteria (LAB) and <i>Bacillus</i> spp., previously isolated from cereals (including mycotoxin-contaminated grains), against the emerging mycotoxin, enniatin B (ENB), and the prevalent mycotoxin, deoxynivalenol (DON). Out of the tested strains, 26 demonstrated notable mycotoxin reduction capabilities, including 2 <i>Bacillus pumilus</i> and 24 <i>Bacillus licheniformis</i> strains. <i>B. licheniformis</i> strains MA572, MA695, MA696, TR174a, TR284, TR363, and TR466a degraded ENB to levels below the detection limit, and six strains reduced DON by 30–35%; <i>B. licheniformis</i> TR251b and TR374 showed the highest DON reduction with 35.7%. The most promising strains for bio-detoxification were <i>B. licheniformis</i> TR284, which achieved a 100% reduction in ENB and a 28.6% reduction in DON and <i>B. licheniformis</i> TR388 with a 97.5% reduction in ENB and a 31.9% reduction in DON. None of the tested LAB strains significantly reduced either mycotoxin. These findings highlight the promising potential of <i>B. licheniformis</i> strains in bio-detoxifying mycotoxin-contaminated cereal products. Further research into the underlying detoxification mechanisms and safety aspects is essential to develop effective bio-detoxification strategies for enhancing food safety.https://www.mdpi.com/2076-2607/12/9/1892mycotoxinsenniatin Bdeoxynivalenollactic acid bacteria<i>Bacillus</i>Fusarium
spellingShingle Sandra Mischler
Amandine André
Irene Chetschik
Susanne Miescher Schwenninger
Potential for the Bio-Detoxification of the Mycotoxins Enniatin B and Deoxynivalenol by Lactic Acid Bacteria and <i>Bacillus</i> spp.
Microorganisms
mycotoxins
enniatin B
deoxynivalenol
lactic acid bacteria
<i>Bacillus</i>
Fusarium
title Potential for the Bio-Detoxification of the Mycotoxins Enniatin B and Deoxynivalenol by Lactic Acid Bacteria and <i>Bacillus</i> spp.
title_full Potential for the Bio-Detoxification of the Mycotoxins Enniatin B and Deoxynivalenol by Lactic Acid Bacteria and <i>Bacillus</i> spp.
title_fullStr Potential for the Bio-Detoxification of the Mycotoxins Enniatin B and Deoxynivalenol by Lactic Acid Bacteria and <i>Bacillus</i> spp.
title_full_unstemmed Potential for the Bio-Detoxification of the Mycotoxins Enniatin B and Deoxynivalenol by Lactic Acid Bacteria and <i>Bacillus</i> spp.
title_short Potential for the Bio-Detoxification of the Mycotoxins Enniatin B and Deoxynivalenol by Lactic Acid Bacteria and <i>Bacillus</i> spp.
title_sort potential for the bio detoxification of the mycotoxins enniatin b and deoxynivalenol by lactic acid bacteria and i bacillus i spp
topic mycotoxins
enniatin B
deoxynivalenol
lactic acid bacteria
<i>Bacillus</i>
Fusarium
url https://www.mdpi.com/2076-2607/12/9/1892
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