Primary and secondary metastatic dissemination: multiple routes to cancer-related death

Primary and secondary metastatic dissemination: multiple routes to cancer-related death

Abstract Metastatic disease accounts for approximately 80% of cancer-related deaths, typically manifesting as single-organ failure mainly through abdominal, cardiovascular, neurological, or respiratory complications. Despite treating thousands of cancer patients daily worldwide, our understanding of...

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Main Authors: D. Sparrer, R. Blazquez, F. Keil, S. Einhell, F. Lüke, S. Uderhardt, C. Gerner, C.H.R. Wendl, M. Proescholdt, C. Schulz, A. Kandulski, S. Haferkamp, H.J. Schlitt, T. Bäuerle, K. Franze, R. Mayr, M. Rechenmacher, P. Hau, D. Hirsch, D. Heudobler, K. Evert, T. Pukrop
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Molecular Cancer
Subjects:
Metastasis
Metastatic dissemination
Bio Therapeutic Goals of Cancer Care Model
Primary dissemination
Secondary dissemination
Cancer-directed therapy
Online Access:https://doi.org/10.1186/s12943-025-02389-5
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