A massively parallel reporter assay library to screen short synthetic promoters in mammalian cells
Abstract Cellular responses to stimuli underpin discoveries in drug development, synthetic biology, and general life sciences. We introduce a library comprising 6144 synthetic promoters, each shorter than 250 bp, designed as transcriptional readouts of cellular stimulus responses in massively parall...
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          | Main Authors: | Adam M. Zahm, William S. Owens, Samuel R. Himes, Braden S. Fallon, Kathleen E. Rondem, Alexa N. Gormick, Joshua S. Bloom, Sriram Kosuri, Henry Chan, Justin G. English | 
|---|---|
| Format: | Article | 
| Language: | English | 
| Published: | Nature Portfolio
    
        2024-11-01 | 
| Series: | Nature Communications | 
| Online Access: | https://doi.org/10.1038/s41467-024-54502-9 | 
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