A new Drosophila model of prolonged inactivity shortens lifespan and impairs muscle function

A new Drosophila model of prolonged inactivity shortens lifespan and impairs muscle function

Abstract Prolonged inactivity due to medical conditions can cause chronic muscle disuse and lead to physical incapacity and poor quality of life. Here, we developed a Drosophila model of confinement inactivity (CI) to observe its effects on lifespan and muscle function. We found that, similar to mam...

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Bibliographic Details
Main Authors: Jodi Protasiewicz, Sarah Snider, Mousumee Khan, Li Tao, Robert J. Wessells, Alyson Sujkowski
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Prolonged inactivity
Confinement
Exercise
Drosophila melanogaster
Online Access:https://doi.org/10.1038/s41598-025-13446-w
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https://doi.org/10.1038/s41598-025-13446-w

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