A biodegradable, microstructured, electroconductive and nano-integrated drug eluting patch (MENDEP) for myocardial tissue engineering

A biodegradable, microstructured, electroconductive and nano-integrated drug eluting patch (MENDEP) for myocardial tissue engineering

We produced a microstructured, electroconductive and nano-functionalized drug eluting cardiac patch (MENDEP) designed to attract endogenous precursor cells, favor their differentiation and counteract adverse ventricular remodeling in situ. MENDEP showed mechanical anisotropy and biaxial strength com...

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Main Authors: Caterina Cristallini, Daniela Rossin, Roberto Vanni, Niccoletta Barbani, Chiara Bulgheresi, Massimiliano Labardi, Sadia Perveen, Silvia Burchielli, Domiziana Terlizzi, Claudia Kusmic, Silvia Del Ry, Manuela Cabiati, Cheherazade Trouki, Dawid Rossino, Francesca Sergi, Anthea Villano, Giovanni D. Aquaro, Giorgia Scarpellino, Federico A. Ruffinatti, Sara Amorim, Ricardo A. Pires, Rui L. Reis, Raffaella Rastaldo, Claudia Giachino
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-08-01
Series:Bioactive Materials
Subjects:
Acellular Electroconductive Cardiac Patch
Cardioprotection
Drug delivery
Molecular imprinting
Myocardial infarction
Cardiac regeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X25001471
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