Prediction of target genes and functional types of cis-regulatory modules in the human genome reveals their distinct properties

Abstract Background Cis-regulatory modules (CRMs) such as enhancers and silencers play critical roles in virtually all biological processes by enhancing and repressing, respectively, the transcription of their target genes in specific cell types. Although numerous CRMs have been predicted in genomes...

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Bibliographic Details
Main Authors: Sisi Yuan, Pengyu Ni, Zhengchang Su
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Biology
Subjects:
Online Access:https://doi.org/10.1186/s12915-025-02313-9
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