Descart: a method for detecting spatial chromatin accessibility patterns with inter-cellular correlations
Abstract Spatial epigenomic technologies enable simultaneous capture of spatial location and chromatin accessibility of cells within tissue slices. Identifying peaks that display spatial variation and cellular heterogeneity is the key analytic task for characterizing the spatial chromatin accessibil...
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Main Authors: | Xiaoyang Chen, Keyi Li, Xiaoqing Wu, Zhen Li, Qun Jiang, Xuejian Cui, Zijing Gao, Yanhong Wu, Rui Jiang |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-12-01
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Series: | Genome Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13059-024-03458-6 |
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