Anemia and polycythemia in patients hospitalised with acute exacerbations of chronic obstructive pulmonary disease: prevalence, patient characteristics, and risk of readmission and mortality
Background Both anemia and polycythemia have previously been shown to influence outcomes in patients with COPD admitted to hospital with acute exacerbations (AECOPD). The aims of this study are to elucidate the prevalence of anemia and polycythemia and their prognostic value on readmission and morta...
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Taylor & Francis Group
2025-12-01
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| Series: | European Clinical Respiratory Journal |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/20018525.2025.2546672 |
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| author | Benedicte B.S. Nielsen Carl-Johan Springborg Peter A Jacobsen Ulla Møller Weinreich |
| author_facet | Benedicte B.S. Nielsen Carl-Johan Springborg Peter A Jacobsen Ulla Møller Weinreich |
| author_sort | Benedicte B.S. Nielsen |
| collection | DOAJ |
| description | Background Both anemia and polycythemia have previously been shown to influence outcomes in patients with COPD admitted to hospital with acute exacerbations (AECOPD). The aims of this study are to elucidate the prevalence of anemia and polycythemia and their prognostic value on readmission and mortality in patients admitted with AECOPD.Methods This retrospective cohort study included patients admitted with AECOPD to hospitals in the North Denmark Region in 2018. Age, gender, body mass index, lung function, smoking history, number of comorbidities, hemoglobin levels, information regarding readmission and mortality were included. Patients were stratified according to hemoglobin levels: Anemia (<12 g/dL in women, <13 g/dL in men), normal hemoglobin (12–15 g/dL in women, 13–17 g/dL in men), and polycythemia (>15 g/dL in women, >17 g/dL in men). Differences in group characteristics, one-year readmission, and mortality risk were investigated.Results In total 1525 subjects with COPD were included at first AECOPD admission in 2018, and divided in anemic, normemic, and polycythemia groups. Prevalence of polycythemia and anemia was 6.8% and 35.2%, respectively. One-year readmission and -mortality risk increased in anemic patients but did not increase in patients with polycythemia.Conclusion Anemia was predictive of increased risk of one-year readmission and -mortality on patients admitted with AECOPD. |
| format | Article |
| id | doaj-art-0b044dfd67da4f5a851c55b0fb0ebf2d |
| institution | Kabale University |
| issn | 2001-8525 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | European Clinical Respiratory Journal |
| spelling | doaj-art-0b044dfd67da4f5a851c55b0fb0ebf2d2025-08-23T15:05:57ZengTaylor & Francis GroupEuropean Clinical Respiratory Journal2001-85252025-12-0112110.1080/20018525.2025.2546672Anemia and polycythemia in patients hospitalised with acute exacerbations of chronic obstructive pulmonary disease: prevalence, patient characteristics, and risk of readmission and mortalityBenedicte B.S. Nielsen0Carl-Johan Springborg1Peter A Jacobsen2Ulla Møller Weinreich3Department of Respiratory Diseases, Aalborg University Hospital, Aalborg, DenmarkDepartment of Respiratory Diseases, Aalborg University Hospital, Aalborg, DenmarkDepartment of Respiratory Diseases, Aalborg University Hospital, Aalborg, DenmarkDepartment of Respiratory Diseases, Aalborg University Hospital, Aalborg, DenmarkBackground Both anemia and polycythemia have previously been shown to influence outcomes in patients with COPD admitted to hospital with acute exacerbations (AECOPD). The aims of this study are to elucidate the prevalence of anemia and polycythemia and their prognostic value on readmission and mortality in patients admitted with AECOPD.Methods This retrospective cohort study included patients admitted with AECOPD to hospitals in the North Denmark Region in 2018. Age, gender, body mass index, lung function, smoking history, number of comorbidities, hemoglobin levels, information regarding readmission and mortality were included. Patients were stratified according to hemoglobin levels: Anemia (<12 g/dL in women, <13 g/dL in men), normal hemoglobin (12–15 g/dL in women, 13–17 g/dL in men), and polycythemia (>15 g/dL in women, >17 g/dL in men). Differences in group characteristics, one-year readmission, and mortality risk were investigated.Results In total 1525 subjects with COPD were included at first AECOPD admission in 2018, and divided in anemic, normemic, and polycythemia groups. Prevalence of polycythemia and anemia was 6.8% and 35.2%, respectively. One-year readmission and -mortality risk increased in anemic patients but did not increase in patients with polycythemia.Conclusion Anemia was predictive of increased risk of one-year readmission and -mortality on patients admitted with AECOPD.https://www.tandfonline.com/doi/10.1080/20018525.2025.2546672Chronic obstructive pulmonary diseaseCOPDexacerbationAECOPDanemiapolycythemia |
| spellingShingle | Benedicte B.S. Nielsen Carl-Johan Springborg Peter A Jacobsen Ulla Møller Weinreich Anemia and polycythemia in patients hospitalised with acute exacerbations of chronic obstructive pulmonary disease: prevalence, patient characteristics, and risk of readmission and mortality European Clinical Respiratory Journal Chronic obstructive pulmonary disease COPD exacerbation AECOPD anemia polycythemia |
| title | Anemia and polycythemia in patients hospitalised with acute exacerbations of chronic obstructive pulmonary disease: prevalence, patient characteristics, and risk of readmission and mortality |
| title_full | Anemia and polycythemia in patients hospitalised with acute exacerbations of chronic obstructive pulmonary disease: prevalence, patient characteristics, and risk of readmission and mortality |
| title_fullStr | Anemia and polycythemia in patients hospitalised with acute exacerbations of chronic obstructive pulmonary disease: prevalence, patient characteristics, and risk of readmission and mortality |
| title_full_unstemmed | Anemia and polycythemia in patients hospitalised with acute exacerbations of chronic obstructive pulmonary disease: prevalence, patient characteristics, and risk of readmission and mortality |
| title_short | Anemia and polycythemia in patients hospitalised with acute exacerbations of chronic obstructive pulmonary disease: prevalence, patient characteristics, and risk of readmission and mortality |
| title_sort | anemia and polycythemia in patients hospitalised with acute exacerbations of chronic obstructive pulmonary disease prevalence patient characteristics and risk of readmission and mortality |
| topic | Chronic obstructive pulmonary disease COPD exacerbation AECOPD anemia polycythemia |
| url | https://www.tandfonline.com/doi/10.1080/20018525.2025.2546672 |
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