Xixin Decoction’s novel mechanism for alleviating Alzheimer’s disease cognitive dysfunction by modulating amyloid-β transport across the blood–brain barrier to reduce neuroinflammation

Xixin Decoction’s novel mechanism for alleviating Alzheimer’s disease cognitive dysfunction by modulating amyloid-β transport across the blood–brain barrier to reduce neuroinflammation

PurposeXixin Decoction (XXD) is a classical formula that has been used to effectively treat dementia for over 300 years. Modern clinical studies have demonstrated its significant therapeutic effects in treating Alzheimer’s disease (AD) without notable adverse reactions. Nevertheless, the specific me...

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Bibliographic Details
Main Authors: Chaokai Yang, Enlong Zhao, Hu Zhang, Liqi Duan, Xinyue Han, Hongli Ding, Yan Cheng, Dengkun Wang, Xiaojing Lei, Yongchang Diwu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Pharmacology
Subjects:
Alzheimer’s disease
Xixin Decoction
blood-brain barrier
amyloid-beta
neuroinflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1508726/full
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https://www.frontiersin.org/articles/10.3389/fphar.2024.1508726/full

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