Detection of PD-L1 expression levels in malignant pleural mesothelioma with a targeted MRI nanoprobe in vivo

Detection of PD-L1 expression levels in malignant pleural mesothelioma with a targeted MRI nanoprobe in vivo

ObjectivesImmune checkpoint inhibitors (ICIs) have demonstrated potential in inhibiting the growth of malignant pleural mesothelioma (MPM), and their efficacy is associated with the expression of programmed death-ligand 1(PD-L1). This study evaluated a PD-L1-targeted nanoprobe for detecting PD-L1 ex...

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Bibliographic Details
Main Authors: Zhenghua Zhang, Yang Tian, Wenjun Gao, Yubin Hu, Liangping Luo, Lichang Lei, Shasha Shen, Dan Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Chemistry
Subjects:
malignant pleural mesothelioma (MPM)
immunotherapy
programmed death ligand 1 (PD-L1)
magnetic resonance imaging (MRI)
nanoprobe
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2024.1508912/full
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https://www.frontiersin.org/articles/10.3389/fchem.2024.1508912/full

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