The Role and the Regulation of NLRP3 Inflammasome in Irritable Bowel Syndrome: A Narrative Review

The Role and the Regulation of NLRP3 Inflammasome in Irritable Bowel Syndrome: A Narrative Review

Irritable bowel syndrome (IBS) is a chronic disorder of the gastrointestinal tract. Its pathogenesis involves multiple factors, including visceral hypersensitivity and immune activation. NLRP3 inflammasome is part of the nucleotide-binding oligomerization domain-like receptor (NLR) family, a crucial...

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Bibliographic Details
Main Authors: Arezina Kasti, Konstantinos Katsas, Maroulla D. Nikolaki, Konstantinos Triantafyllou
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Microorganisms
Subjects:
irritable bowel syndrome
NLRP3 inflammasome
visceral hypersensitivity
proinflammatory cytokines
Online Access:https://www.mdpi.com/2076-2607/13/1/171
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