Afucosylated IgG in idiopathic nephrotic syndrome patients with anti-nephrin autoantibodies correlate with disease activity

Afucosylated IgG in idiopathic nephrotic syndrome patients with anti-nephrin autoantibodies correlate with disease activity

Background: Idiopathic nephrotic syndrome (INS) is a glomerular disorder characterized by podocyte injury and proteinuria. Emerging evidence suggests that anti-nephrin autoantibodies (Abs) may contribute to disease pathogenesis in a subset of INS patients. Variation in techniques for detecting anti-...

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Main Authors: Sonia Spinelli, Andrea Garbarino, Francesca Lugani, Edoardo La Porta, Noemi Rumeo, Giorgio Piaggio, Alberto Magnasco, Antonella Trivelli, Maria Ludovica Degl’Innocenti, Gino Tripodi, Simona Granata, Francesca Leone, Elena Zocchi, Lorenzo Gallon, Gian Marco Ghiggeri, Enrico Verrina, Gianluigi Zaza, Giovanni Candiano, Maurizio Bruschi
Format: Article
Language:English
Published: Elsevier 2025-12-01
Series:Journal of Translational Autoimmunity
Online Access:http://www.sciencedirect.com/science/article/pii/S2589909025000425
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