Effect of 2-Aminoethoxydiphenyl Borate on the State of Skeletal Muscles in Dystrophin-Deficient mdx Mice

Effect of 2-Aminoethoxydiphenyl Borate on the State of Skeletal Muscles in Dystrophin-Deficient mdx Mice

Objective: Ca2+ overload of muscle fibers is one of the factors that secondarily aggravate the development of Duchenne muscular dystrophy (DMD). The purpose of this study is to evaluate the effects of the Ca2+ channel modulator 2-aminoethoxydiphenyl borate (APB) on skeletal muscle...

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Bibliographic Details
Main Authors: Mikhail V. Dubinin, Anastasia E. Stepanova, Anastasia D. Igoshkina, Irina B. Mikheeva, Eugeny Yu. Talanov, Alena A. Cherepanova, Konstantin N. Belosludtsev
Format: Article
Language:English
Published: IMR Press 2024-12-01
Series:Frontiers in Bioscience-Landmark
Subjects:
2-aminoethoxydiphenyl borate
duchenne muscular dystrophy
mdx mice
skeletal muscles
mitochondria
calcium
Online Access:https://www.imrpress.com/journal/FBL/29/12/10.31083/j.fbl2912428
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https://www.imrpress.com/journal/FBL/29/12/10.31083/j.fbl2912428

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