PSMA-Directed Radioligand Therapy for Metastatic Prostate Cancer
Prostate cancer is the leading cause of total years of life lost due to cancer in men, despite developments in treatment and technology. Improved outcomes and novel therapy concepts, such as theranostics, are urgently needed. A typical example of theranostics, defined as a combination of therapy and...
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| Format: | Article |
| Language: | English |
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THE HEALTHBOOK COMPANY LTD.
2023-12-01
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| Series: | healthbook TIMES. Oncology Hematology |
| Online Access: | https://doi.org/10.36000/HBT.OH.2023.18.130 |
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| author | Ellen Heitlinger |
| author_facet | Ellen Heitlinger |
| author_sort | Ellen Heitlinger |
| collection | DOAJ |
| description | Prostate cancer is the leading cause of total years of life lost due to cancer in men, despite developments in treatment and technology. Improved outcomes and novel therapy concepts, such as theranostics, are urgently needed. A typical example of theranostics, defined as a combination of therapy and diagnostic, is the use of radiolabeled ligands that bind to a specific target on a cancer cell and emit radiation, allowing treatment planning, dosimetry and imaging using positron emission tomography (PET). Some radioligands, such as ^177^Lu-PSMA-617, can also emit β-radiation which leads to apoptosis of tumor cells. At the Swiss Oncology and Hematology Congress (SOHC) 2023, Prof. Dr Wolfgang Fendler from Essen and Prof. Dr Irene Burger from Zurich discussed results from the studies assessing ^177^Lu-PSMA-617 and ^177^Lu-PSMA-other ligands as a treatment for patients with prostate cancer.
PEER REVIEWED ARTICLE |
| format | Article |
| id | doaj-art-089a080a8c5b4a528bcd2643ed66aa87 |
| institution | Kabale University |
| issn | 2673-2106 |
| language | English |
| publishDate | 2023-12-01 |
| publisher | THE HEALTHBOOK COMPANY LTD. |
| record_format | Article |
| series | healthbook TIMES. Oncology Hematology |
| spelling | doaj-art-089a080a8c5b4a528bcd2643ed66aa872024-12-12T17:11:07ZengTHE HEALTHBOOK COMPANY LTD.healthbook TIMES. Oncology Hematology2673-21062023-12-01184PSMA-Directed Radioligand Therapy for Metastatic Prostate CancerEllen HeitlingerProstate cancer is the leading cause of total years of life lost due to cancer in men, despite developments in treatment and technology. Improved outcomes and novel therapy concepts, such as theranostics, are urgently needed. A typical example of theranostics, defined as a combination of therapy and diagnostic, is the use of radiolabeled ligands that bind to a specific target on a cancer cell and emit radiation, allowing treatment planning, dosimetry and imaging using positron emission tomography (PET). Some radioligands, such as ^177^Lu-PSMA-617, can also emit β-radiation which leads to apoptosis of tumor cells. At the Swiss Oncology and Hematology Congress (SOHC) 2023, Prof. Dr Wolfgang Fendler from Essen and Prof. Dr Irene Burger from Zurich discussed results from the studies assessing ^177^Lu-PSMA-617 and ^177^Lu-PSMA-other ligands as a treatment for patients with prostate cancer. PEER REVIEWED ARTICLEhttps://doi.org/10.36000/HBT.OH.2023.18.130 |
| spellingShingle | Ellen Heitlinger PSMA-Directed Radioligand Therapy for Metastatic Prostate Cancer healthbook TIMES. Oncology Hematology |
| title | PSMA-Directed Radioligand Therapy for Metastatic Prostate Cancer |
| title_full | PSMA-Directed Radioligand Therapy for Metastatic Prostate Cancer |
| title_fullStr | PSMA-Directed Radioligand Therapy for Metastatic Prostate Cancer |
| title_full_unstemmed | PSMA-Directed Radioligand Therapy for Metastatic Prostate Cancer |
| title_short | PSMA-Directed Radioligand Therapy for Metastatic Prostate Cancer |
| title_sort | psma directed radioligand therapy for metastatic prostate cancer |
| url | https://doi.org/10.36000/HBT.OH.2023.18.130 |
| work_keys_str_mv | AT ellenheitlinger psmadirectedradioligandtherapyformetastaticprostatecancer |