Assessment of Growth Disturbance in Japanese Children with IBD
In Japan, there is as yet no report on growth retardation in children with IBD. We therefore investigated the cause of growth retardation in Japanese children with IBD. We investigated the height, body weight, serum levels of albumin, IGF-I, CRP, and cytokines, and the amount of corticosteroid admin...
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | International Journal of Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2010/958915 |
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| author | Tetsuo Shono Mayuko Kato Yo Aoyagi Hidenori Haruna Tohru Fujii Takahiro Kudo Yoshikazu Ohtsuka Toshiaki Shimizu |
| author_facet | Tetsuo Shono Mayuko Kato Yo Aoyagi Hidenori Haruna Tohru Fujii Takahiro Kudo Yoshikazu Ohtsuka Toshiaki Shimizu |
| author_sort | Tetsuo Shono |
| collection | DOAJ |
| description | In Japan, there is as yet no report on growth retardation in children with IBD. We therefore investigated the cause of growth retardation in Japanese children with IBD. We investigated the height, body weight, serum levels of albumin, IGF-I, CRP, and cytokines, and the amount of corticosteroid administered in children with Crohn's disease (CD, 𝑛=15) and ulcerative colitis (UC, 𝑛=18). Our results suggest that growth retardation is already present before the initial visit in children with CD, and chronic inflammation may be responsible this growth disturbance. Moreover, the amount of PSL used may contribute to growth retardation by decreasing the serum levels of IGF-I in children with IBD. |
| format | Article |
| id | doaj-art-0858a54d0a9b46dfbfa9b245281cf80c |
| institution | Kabale University |
| issn | 1687-9740 1687-9759 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Pediatrics |
| spelling | doaj-art-0858a54d0a9b46dfbfa9b245281cf80c2025-08-20T03:55:32ZengWileyInternational Journal of Pediatrics1687-97401687-97592010-01-01201010.1155/2010/958915958915Assessment of Growth Disturbance in Japanese Children with IBDTetsuo Shono0Mayuko Kato1Yo Aoyagi2Hidenori Haruna3Tohru Fujii4Takahiro Kudo5Yoshikazu Ohtsuka6Toshiaki Shimizu7Department of Pediatrics, Juntendo University School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-8421, JapanDepartment of Pediatrics, Juntendo University School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-8421, JapanDepartment of Pediatrics, Juntendo University School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-8421, JapanDepartment of Pediatrics, Juntendo University School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-8421, JapanDepartment of Pediatrics, Juntendo University School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-8421, JapanDepartment of Pediatrics, Juntendo University School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-8421, JapanDepartment of Pediatrics, Juntendo University School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-8421, JapanDepartment of Pediatrics, Juntendo University School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-8421, JapanIn Japan, there is as yet no report on growth retardation in children with IBD. We therefore investigated the cause of growth retardation in Japanese children with IBD. We investigated the height, body weight, serum levels of albumin, IGF-I, CRP, and cytokines, and the amount of corticosteroid administered in children with Crohn's disease (CD, 𝑛=15) and ulcerative colitis (UC, 𝑛=18). Our results suggest that growth retardation is already present before the initial visit in children with CD, and chronic inflammation may be responsible this growth disturbance. Moreover, the amount of PSL used may contribute to growth retardation by decreasing the serum levels of IGF-I in children with IBD.http://dx.doi.org/10.1155/2010/958915 |
| spellingShingle | Tetsuo Shono Mayuko Kato Yo Aoyagi Hidenori Haruna Tohru Fujii Takahiro Kudo Yoshikazu Ohtsuka Toshiaki Shimizu Assessment of Growth Disturbance in Japanese Children with IBD International Journal of Pediatrics |
| title | Assessment of Growth Disturbance in Japanese Children with IBD |
| title_full | Assessment of Growth Disturbance in Japanese Children with IBD |
| title_fullStr | Assessment of Growth Disturbance in Japanese Children with IBD |
| title_full_unstemmed | Assessment of Growth Disturbance in Japanese Children with IBD |
| title_short | Assessment of Growth Disturbance in Japanese Children with IBD |
| title_sort | assessment of growth disturbance in japanese children with ibd |
| url | http://dx.doi.org/10.1155/2010/958915 |
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