Mesenchymal stem cells and their exosomes mitigate osteoarthritis by restoring the balance between proinflammatory Teffs and Tregs

Osteoarthritis (OA) is a degenerative joint disease caused by chronic inflammation that damages articular cartilage. In addition to the wear and tear of joints, aberrant remodelling driven by a significant presence of inflammatory mediators within the joint is one of the key mechanisms in the pathog...

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Bibliographic Details
Main Authors: Tianhao Liu, Chunxiao Ran, Dewei Zhao, Fan Yang, Qiang Guo, Jiahui Yang, Xiuzhi Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Aging
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Online Access:https://www.frontiersin.org/articles/10.3389/fragi.2024.1509014/full
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