Comparative evaluation of live attenuated and killed tachyzoites as vaccine candidates for toxoplasmosis

Comparative evaluation of live attenuated and killed tachyzoites as vaccine candidates for toxoplasmosis

Abstract Toxoplasma gondii (T.gondii) an obligate intracellular protozoan, causes toxoplasmosis, leading to significant economic losses and posing serious public health challenges worldwide. Developing an effective vaccine for toxoplasmosis in humans remains difficult. In this study, we evaluated th...

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Main Authors: Eman E. El Shanawany, Eman H. Abdel-Rahman, Waleed A. Nemr, Soad E. Hassan, Noha M. F. Hassan, Hassan M. Desouky, Rabab Zalat, Amany Ebrahim Nofal, Raafat M. Shaapan, Salwa Sami Younis
Format: Article
Language:English
Published: SpringerOpen 2025-07-01
Series:AMB Express
Subjects:
Gamma irradiation
Vaccine
Live attenuated tachhyzoites
Toxoplasma gondii
Mice
Acute toxoplasmosis
Online Access:https://doi.org/10.1186/s13568-025-01889-3
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https://doi.org/10.1186/s13568-025-01889-3

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