Identification of blood transcriptome modules associated with suicidal ideation in patients with major depressive disorder

Identification of blood transcriptome modules associated with suicidal ideation in patients with major depressive disorder

Abstract The risk of suicide in patients with major depressive disorder (MDD) poses a major concern, with studies suggesting that genetics may be a contributing factor. Although there are many transcriptomic studies on postmortem brain tissue related to suicidal behavior, the blood transcriptional m...

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Bibliographic Details
Main Authors: Min Wang, Hailin Xiang, Jinxue Wei, Yikai Dou, Yushun Yan, Yue Du, Huanhuan Fan, Liansheng Zhao, Rongjun Ni, Xiao Yang, Xiaohong Ma
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Major depressive disorder
Suicidal ideation
Transcriptome
Weighted gene coexpression network analysis
Immunity
Energy metabolism
Online Access:https://doi.org/10.1038/s41598-025-85431-2
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