Mitigating environmental toxicity with hydrogen nanobubbles: A mitochondrial function-based approach to ecological restoration
In biological systems, nanobubbles (NBs) effectively enhance hydrogen molecule retention and scavenging reactive oxygen species (ROS), but the underlying mechanisms remain elusive. To investigate this, we prepared hydrogen NB water samples with consistent dissolved hydrogen levels but varying NB den...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-11-01
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| Series: | Environment International |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0160412024007128 |
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| author | Han Bao You Zhang Shuang Lv Shu Liu Wenhong Fan |
| author_facet | Han Bao You Zhang Shuang Lv Shu Liu Wenhong Fan |
| author_sort | Han Bao |
| collection | DOAJ |
| description | In biological systems, nanobubbles (NBs) effectively enhance hydrogen molecule retention and scavenging reactive oxygen species (ROS), but the underlying mechanisms remain elusive. To investigate this, we prepared hydrogen NB water samples with consistent dissolved hydrogen levels but varying NB densities to explore their physicochemical properties and effects on green algae (Chlorella vulgaris) under oxidative stress induced by copper ions (Cu2+) and cadmium ions (Cd2+). The results indicated a strong correlation between the hydrogen NB number density and the 25 % inhibitory concentration of Cu2+ over 24 h, with ROS removal efficiency increased with the NB number density. Gas chromatography showed that the hydrogen NBs in the solution had a high gas density that enhanced hydrogen transport into C. vulgaris. With regard to mitochondrial activity, hydrogen NBs were observed to enhance the function of mitochondrial complexes I and V and increase the mitochondrial membrane potential. Experiments with C. vulgaris mitochondrial electrodes showed that the electron transfer rates increased significantly in the presence of hydrogen NBs. We concluded that the high gas density of hydrogen NBs augments intracellular hydrogen delivery and strengthens mitochondrial functions. |
| format | Article |
| id | doaj-art-05f30672bd8347cda9adceb6e371ec5e |
| institution | Kabale University |
| issn | 0160-4120 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Environment International |
| spelling | doaj-art-05f30672bd8347cda9adceb6e371ec5e2024-11-22T07:35:51ZengElsevierEnvironment International0160-41202024-11-01193109126Mitigating environmental toxicity with hydrogen nanobubbles: A mitochondrial function-based approach to ecological restorationHan Bao0You Zhang1Shuang Lv2Shu Liu3Wenhong Fan4School of Materials Science and Engineering, Beihang University, Beijing 100191, ChinaSchool of Materials Science and Engineering, Beihang University, Beijing 100191, ChinaSchool of Materials Science and Engineering, Beihang University, Beijing 100191, ChinaSchool of Materials Science and Engineering, Beihang University, Beijing 100191, China; Corresponding author.School of Materials Science and Engineering, Beihang University, Beijing 100191, China; Beijing Advanced Innovation Center for Big Data-Based Precision Medicine, Beihang University, Beijing 100191, ChinaIn biological systems, nanobubbles (NBs) effectively enhance hydrogen molecule retention and scavenging reactive oxygen species (ROS), but the underlying mechanisms remain elusive. To investigate this, we prepared hydrogen NB water samples with consistent dissolved hydrogen levels but varying NB densities to explore their physicochemical properties and effects on green algae (Chlorella vulgaris) under oxidative stress induced by copper ions (Cu2+) and cadmium ions (Cd2+). The results indicated a strong correlation between the hydrogen NB number density and the 25 % inhibitory concentration of Cu2+ over 24 h, with ROS removal efficiency increased with the NB number density. Gas chromatography showed that the hydrogen NBs in the solution had a high gas density that enhanced hydrogen transport into C. vulgaris. With regard to mitochondrial activity, hydrogen NBs were observed to enhance the function of mitochondrial complexes I and V and increase the mitochondrial membrane potential. Experiments with C. vulgaris mitochondrial electrodes showed that the electron transfer rates increased significantly in the presence of hydrogen NBs. We concluded that the high gas density of hydrogen NBs augments intracellular hydrogen delivery and strengthens mitochondrial functions.http://www.sciencedirect.com/science/article/pii/S0160412024007128Nanobubble number densityMitochondrialCopperOxidative stressAlgaeHydrogen content |
| spellingShingle | Han Bao You Zhang Shuang Lv Shu Liu Wenhong Fan Mitigating environmental toxicity with hydrogen nanobubbles: A mitochondrial function-based approach to ecological restoration Environment International Nanobubble number density Mitochondrial Copper Oxidative stress Algae Hydrogen content |
| title | Mitigating environmental toxicity with hydrogen nanobubbles: A mitochondrial function-based approach to ecological restoration |
| title_full | Mitigating environmental toxicity with hydrogen nanobubbles: A mitochondrial function-based approach to ecological restoration |
| title_fullStr | Mitigating environmental toxicity with hydrogen nanobubbles: A mitochondrial function-based approach to ecological restoration |
| title_full_unstemmed | Mitigating environmental toxicity with hydrogen nanobubbles: A mitochondrial function-based approach to ecological restoration |
| title_short | Mitigating environmental toxicity with hydrogen nanobubbles: A mitochondrial function-based approach to ecological restoration |
| title_sort | mitigating environmental toxicity with hydrogen nanobubbles a mitochondrial function based approach to ecological restoration |
| topic | Nanobubble number density Mitochondrial Copper Oxidative stress Algae Hydrogen content |
| url | http://www.sciencedirect.com/science/article/pii/S0160412024007128 |
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