SPAT inhibits LUAD metastasis by targeting SF1-mediated splicing

SPAT inhibits LUAD metastasis by targeting SF1-mediated splicing

Abstract Lung adenocarcinoma (LUAD) progression involves alterations in oncogenes and tumor suppressor genes, collectively shaping tumorigenic landscape. However, the precise interactions within this landscape remain inadequately understood. Here, we present a functional characterization of a novel...

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Main Authors: Yun Ma, Xiaoxu Zhou, Mengqian Yu, Xiang Cheng, Juze Yang, Jiayi Ren, Chengcai Zheng, Jia Li, Xinyi Qian, Jiani Yi, Honghe Zhang, Yan Lu, Pengyuan Liu
Format: Article
Language:English
Published: Nature Publishing Group 2025-08-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07924-2
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https://doi.org/10.1038/s41419-025-07924-2

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