Statistical methods in the analysis of multicentre HIV randomized controlled trials in the African region: a scoping review

Abstract Background The majority of phase 3 clinical trials are implemented in multiple sites or centres, which inevitably leads to a correlation between observations from the same site or centre. This correlation must be carefully considered in both the design and the statistical analysis to ensure...

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Bibliographic Details
Main Authors: Mikateko Mazinu, Nomonde Gwebushe, Samuel Manda, Tarylee Reddy
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Medical Research Methodology
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Online Access:https://doi.org/10.1186/s12874-024-02441-w
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