Damage to white matter networks resulting from small vessel disease and the effects on cognitive function

Damage to white matter networks resulting from small vessel disease and the effects on cognitive function

Abstract White matter hyperintensities (WMHs) are prevalent in older age and are associated with cognitive decline. The location and extent of WMHs likely influences the relationship with behavior. Identifying which tracts are more likely impacted by WMHs might enable better understanding of which b...

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Main Authors: Natalie Busby, Janina Wilmskoetter, Roger Newman-Norlund, Sarah Newman-Norlund, Sara Sayers, Sarah C. Wilson, Nicholas Riccardi, Alex Teghipco, Rebecca W. Roth, Lumi Bakos, Chris Rorden, Julius Fridriksson, Leonardo Bonilha
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
White matter hyperintensities
Structural connectivity
Aging
Brain health
Cognition
Online Access:https://doi.org/10.1038/s41598-025-13813-7
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https://doi.org/10.1038/s41598-025-13813-7

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