Strategies for specific multimodal imaging of cancer-associated fibroblasts and applications in theranostics of cancer

Strategies for specific multimodal imaging of cancer-associated fibroblasts and applications in theranostics of cancer

Fibroblast activating protein (FAP) is up-regulated in cancer-associated fibroblasts (CAFs) of more than 90 % of tumor microenvironment and also highly expressed on the surface of multiple tumor cells like glioblastoma, which can be used as a specific target for tumor diagnosis and treatment. At pre...

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Bibliographic Details
Main Authors: Li Wen, Chengxue He, Yanhui Guo, Nina Zhou, Xiangxi Meng, Yuwen Chen, Cheng Ma, Hua Zhu, Zhi Yang, Lei Xia
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Materials Today Bio
Subjects:
Fibroblast activating protein
Melanin nanoparticles
Multimodal imaging
Theranostics
Radioisotope therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006424004812
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