Iron-based MOF with Catalase-like activity improves the synergistic therapeutic effect of PDT/ferroptosis/starvation therapy by reversing the tumor hypoxic microenvironment

Iron-based MOF with Catalase-like activity improves the synergistic therapeutic effect of PDT/ferroptosis/starvation therapy by reversing the tumor hypoxic microenvironment

Abstract Reversing the hypoxic microenvironment of tumors is an important method to enhance the synergistic effect of tumor treatment. In this work, we developed the nanoparticles called Ce6@HGMOF, which consists of a photosensitizer (Ce6), glucose oxidase (GOX), chemotherapy drugs (HCPT) and an iro...

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Bibliographic Details
Main Authors: Yukun Chen, Yuanyuan Chen, Zhenzhi Wang, Lian Yang, Yu Zhang, Zhanxia Zhang, Lijun Jia
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Nanobiotechnology
Subjects:
Tumor hypoxia
Synergistic treatment
Antitumor
Nano-drug delivery systems
Online Access:https://doi.org/10.1186/s12951-024-02921-7
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https://doi.org/10.1186/s12951-024-02921-7

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