Gentiopicroside improves DSS-induced ulcerative colitis and secondary liver injury in mice by enhancing the intestinal barrier and regulating the gut microbiome

Gentiopicroside improves DSS-induced ulcerative colitis and secondary liver injury in mice by enhancing the intestinal barrier and regulating the gut microbiome

Abstract Ulcerative colitis (UC) is a chronic inflammatory bowel disease frequently accompanied by intestinal barrier dysfunction and gut microbiome dysbiosis. Emerging evidence suggests that these impairments can contribute to secondary liver injury (SLI) by disrupting the gut–liver axis and promot...

Full description

Saved in:
Bibliographic Details
Main Authors: Liu Cao, Mengyuan Niu, Xiaoqing Tang, Yiting Wang, Xianjing Hu, Weibo Dai
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Gentiopicroside
Ulcerative colitis
Intestinal barrier
Gut Microbiome
Secondary liver injury
Online Access:https://doi.org/10.1038/s41598-025-12255-5
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/s41598-025-12255-5

Similar Items