Fabrication and in vitro evaluation of pH/thermo dual responsive hydrogels as controlled ibuprofen sodium in situ depot

Fabrication and in vitro evaluation of pH/thermo dual responsive hydrogels as controlled ibuprofen sodium in situ depot

Ibuprofen sodium (IBP) is a commonly used NSAID for multiple pain conditions. However, despite its extensive use, it is associated with multiple GIT adverse effects after oral administration. In the present study, we have fabricated thermoresponsive gel depot using Poly (N-vinylcaprolactam) and sodi...

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Bibliographic Details
Main Authors: Samiullah Khan, Abdur Rehman, Syed Faisal Badshah, Gamal A. Shazly, Amira Metouekel, Fakhreldeen Dabiellil
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Designed Monomers and Polymers
Subjects:
thermogels
poly(n-vinylcaprolactam)
sodium alginate
in situ depot
rheology
mtt assay
Online Access:http://dx.doi.org/10.1080/15685551.2024.2442118
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http://dx.doi.org/10.1080/15685551.2024.2442118

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