Cross-genotype immunogenicity and antibody-dependent enhancement of KD-382 dengue vaccine in flavivirus-naïve adults

Abstract This exploratory study evaluated the neutralization breadth and potential antibody-dependent enhancement (ADE) risk following a single-dose of the KD-382 live-attenuated tetravalent dengue vaccine over 12 months in flavivirus-naïve healthy adults. Using single-round infectious particles rep...

Full description

Saved in:
Bibliographic Details
Main Authors: Jean Claude Balingit, Motoharu Abe, Ryosuke Suzuki, Dalouny Xayavong, Mya Myat Ngwe Tun, Yuki Takamatsu, Kengo Sonoda, Kouichi Morita
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-025-01204-y
Tags: Add Tag
No Tags, Be the first to tag this record!