Induction of systemic and mucosal immune response against Zika virus by vaccination with non-infectious chimeric VLPs

Induction of systemic and mucosal immune response against Zika virus by vaccination with non-infectious chimeric VLPs

Abstract The Zika virus (ZIKV) causes acute febrile illness and can lead to complications such as Guillain-Barré syndrome and congenital disorders. As arbovirus outbreaks increase, vaccination becomes a crucial preventive strategy. Currently, no commercial vaccines are available for ZIKV, which is t...

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Bibliographic Details
Main Authors: Luciana Agostina Fassola, Lucía Lara Rupil, Florencia Martínez, Guillermo Albrieu-Llinás, Marianela del Carmen Serradell
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Arbovirus
Zika virus
Subunit vaccines
Mucosal response
Online Access:https://doi.org/10.1038/s41598-025-07059-6
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