EFFECTS OF γс-CYTOKINES (IL-2, IL-7 AND IL-15) UPON IN VITRO MATURATION AND DIFFERENTIATION OF CD4<sup>+</sup>CD45RО<sup>+</sup>/CD8<sup>+</sup>CD45RО<sup>+</sup> T CELLS

EFFECTS OF γс-CYTOKINES (IL-2, IL-7 AND IL-15) UPON IN VITRO MATURATION AND DIFFERENTIATION OF CD4<sup>+</sup>CD45RО<sup>+</sup>/CD8<sup>+</sup>CD45RО<sup>+</sup> T CELLS

Effect of γс-cytokines (IL-2, IL-7 и IL-15) upon maturation and differentiation of cytotoxic and helper CD45RО+ Tcell population was studied in the homeostatic in vitro culture conditions. We have found that IL-2, IL-7 and IL-15 mediate maturation and differentiation of CD8 T cells central memory, r...

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Bibliographic Details
Main Authors: K. A. Yurova, O. G. Khaziakhmatova, N. M. Todosenko, L. S. Litvinova
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2018-01-01
Series:Медицинская иммунология
Subjects:
immunological memory
central memory t cells
effector memory t cells
terminally differentiated cells
γc-cytokines
differentiation
Online Access:https://www.mimmun.ru/mimmun/article/view/1431
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