Optimal time and volume of fluid resuscitation in patients with sepsis: a nationwide multicenter cohort study

Abstract The optimal fluid resuscitation strategy for managing sepsis remains unknown. We aimed to examine the independent and joint associations of infusion time and volume of fluid resuscitation on mortality in patients with sepsis. We analyzed adult patients with sepsis who received > 20 mL/kg...

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Main Authors: Dong-gon Hyun, Jee Hwan Ahn, Jin Won Huh, Sang-Bum Hong, Younsuck Koh, Dong Kyu Oh, Su Yeon Lee, Mi Hyeon Park, Chae-Man Lim, the Korean Sepsis Alliance (KSA) Investigators
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-14854-8
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