A phase separation-related gene signature for prognosis prediction and immunotherapy response evaluation in gastric cancer with targeted natural compound discovery

A phase separation-related gene signature for prognosis prediction and immunotherapy response evaluation in gastric cancer with targeted natural compound discovery

Abstract Background Aberrant phase separation (PS) has emerged as a pivotal pathogenic mechanism in cancer development. However, its prognostic significance and influence on the tumor immune microenvironment in gastric cancer (GC) remain largely unexplored. This study aimed to develop a PS-related r...

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Bibliographic Details
Main Authors: Yanjuan Jia, Yuanyuan Ma, Zhenhao Li, Wenze Zhang, Rukun Lu, Wanxia Wang, Chaojun Wei, Chunyan Wei, Yonghong Li, Xiaoling Gao, Tao Qu
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Discover Oncology
Subjects:
Phase separation
Gastric cancer
Immunotherapy response
Natural small molecules
Online Access:https://doi.org/10.1007/s12672-025-03129-3
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https://doi.org/10.1007/s12672-025-03129-3

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